Post Doctorate Fellows - Shingo Kuroda

Immediate implant loading produces micromotion at the bone-implant interface, which can lead to fibrous or fibrocartilaginous encapsulation and implant failure. There is an incomplete understanding of the key physical factors and underlying mechanisms that influence cell fate decisions at the bone-implant interface. Our working hypothesis is that deformation in healing tissue regulates cell fate decisions at the bone-implant interface. To test this hypothesis, we try to implant a micromotion device in an animal model and measure the cellular response to different mechanical stimuli using molecular, cellular, and genetic approaches. Our project will contribute scientific insight that can guide placement and design decisions with skeletal implants.

• Professional experience

(2008-Present) Associate Professor, Department of Orthodontics and Dentofacial Orthopedics, The Tokushima University Graduate School of Oral Sciences, Japan.

(2000-2008) Assistant Professor, Department of Orthodontics and Dentofacial Orthopedics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan.

• Education

(1996-2000) Doctor of Philosophy in Dental Science , Doctoral program, Osaka University Graduate School of Dentistry, Japan.

(1990-1996) Doctor of Dental Surgery, Osaka University, Japan.

• Publications

Kuroda S, Tanimoto K, Izawa T, Fujihara S, Koolstra JH, Tanaka E. (2009): Biomechanical and biochemical characteristics of the mandibular condylar cartilage. Osteoarthritis and Cartilage, 17:1408-1415

Takano-Yamamoto T, Kuroda S. (2009): Diagnostic et traitement de patients adultes présentant une asymétrie faciale. L'Orthodontie Française, 80:313-329.

Kuroda S, Tanaka E. Application of TADs for treatment of adult Class III malocclusion. Seminars in Orthodontics, in press.

Kuroda S, Fujii A, Sugie M, Uoi S, Kondo K, Ando R, Yamashiro T. Relationships between orthodontic expertise and perception of treatment needs for maxillary protrusion: comparison of dental students, residents, and orthodontists. Am J Orthod Dentofacial Orthop, in press.

Kuroda S, Okada T, Ishimitsu T, Tanimoto Y, Miyawaki S, Takano-Yamamoto T. (2009): Longitudinal craniofacial changes in subjects with untreated maxillary protrusion and mandibular protrusions in the third decade of life. Orthod Waves, 68: in press.

Kuroda Y, Kuroda S, Alexander RG, Tanaka E. Adult Class III treatment using a J-hook headgear to the mandibular arch. Angle Orthod, in press.

Yanagita T, Kuroda S, Takano-Yamamoto T, Yamashiro T. Class III malocclusion with complex problems of lateral open bite and severe crowding successfully treated using miniscrew anchorage and lingual orthodontic brackets. Am J Orthod Dentofacial Orthop, in press.

Ohura R, Kuroda S, Takahashi T, Kondo Y, Tanaka E. Efficient usage of implant anchorage in treatment of Angle Class II malocclusion with overerupted maxillary first molar and mesially inclined mandibular molars. Am J Orthod Dentofacial Orthop, in press.

Hashimoto T, Fukunaga T, Kuroda S, Sakai Y, Yamashiro T, Takano-Yamamoto T. Mandibular deviation and canted maxillary occlusal plane treated with miniscrews and intraoral vertical ramus osteotomy: Functional and morphologic changes. Am J Orthod Dentofacial Orthop, in press.

Kondo Y, Takahashi T, Oba Y, Kuroda S, Moriyama K, Tanaka E. (2009): Blood flow distribution of repaired lip in cleft lip patients. Angle Orthod, 79:1182-1187.

Sakai Y, Kuroda S, Tamamura N, Yamashiro T, Takano-Yamamoto T. (2009): A case of severe crowding with nickel allergy treated using non-nickel-containing orthodontic appliances. Orthodontic Waves, 68:129-136.

Nishio C, Tanimoto K, Hirose M, Horiuchi S, Kuroda S, Tanne K, Tanaka E. (2009): Stress analysis in the mandibular condyle during prolonged clenching: a theoretical approach with the finite-element method. Proc Inst Mech Eng Part H-J Eng Med, 223:739-748.

Kitase Y, Yokozeki, Fujihara S, Izawa T, Kuroda S, Tanimoto K, Moriyama K, Tanaka E. (2009): Analysis of gene expression profiles in human periodontal ligament cells under hypoxia: The protective effect of CC chemokine ligand 2 to oxygen shortage. Arch Oral Biol, 54:618-624.

Kuroda S, Murakami K, Morishige Y, Takano-Yamamoto T. (2009): Severe Class II malocclusion with facial asymmetry treated with intra-oral vertico-sagittal ramus osteotomy and LeFort I osteotomy. Am J Orthod Dentofacial Orthop, 135:809-819.

Tamamura N, Kuroda S, Sugawara Y, Takano-Yamamoto T, Yamashiro T. (2009): Use of palatal miniscrew anchorage and lingual multi-bracket appliances to enhance efficiency of molar scissors-bite correction. Angle Orthod, 79:577-584

Sakai Y, Balam TA, Kuroda S, Tamamura N, Fukunaga T, Takigawa M, Takano-Yamamoto T. (2009): CTGF and apoptosis in mouse osteocytes induced by tooth movement. J Dent Res, 88:345-350.

Hashimoto T, Kuroda S, Kamioka H, Mishima K, Sugahara T, Takano-Yamamoto T. (2009): Bimaxillary protrusion with massater muscle hypertrophy treated with titanium screw anchorage and masseter surgical reduction. Am J Orthod Dentofacial Orthop, 135:536-548.

Kuroda S, Yamada K, Deguchi T, Kyung HM, Takano-Yamamoto T. (2009): Class II malocclusion treated with miniscrew anchorage: comparison with traditional orthodontic mechanics outcomes. Am J Orthod Dentofacial Orthop, 135:302-309.

Yamada K, Kuroda S, Deguchi T, Takano-Yamamoto T, Yamashiro T. (2009): Distal movement of maxillary molars using miniscrew anchorage in the buccal interradicular region. Angle Orthod, 79:78-84.

Kuroda S, Sugahara T, Takabatake S, Taketa H, Ando R, Yamada K, Takano-Yamamoto T. (2009): Influence of anteroposterior mandibular positions on facial attractiveness in Japanese adults. Am J Orthod Dentofacial Orthop, 135:73-78.

Hashimoto T, Kuroda S, Lihua E, Tanimoto Y, Miyawaki S, Takano-Yamamoto T. (2008): Correlation between craniofacial and condylar path asymmetry. J Oral Maxillofacial Surg, 66:2020-2027.

Deguchi T, Murakami T, Kuroda S, Yabuuchi T, Kamioka H, Takano-Yamamoto T. (2008): Comparison of the intrusion effects on the maxillary incisors between implant anchorage and J-hook headgear. Am J Orthod Dentofacial Orthop, 133:654-660.

Sugawara Y, Kuroda S, Tamamura N, Takano-Yamamoto T. (2008): Adult patient with mandibular protrusion and unstable occlusion treated using titanium screw anchorage. Am J Orthod Dentofacial Orthop, 133:102-111.

Sakai Y, Kuroda S, Murshid SA, Takano-Yamamoto T. (2008): Skeletal Class III severe open bite treatment using implant anchorage. Angle Orthod, 78:157-166.

Kuroda S, Sakai Y, Tamamura N, Deguchi T, Takano-Yamamoto T. (2007): Treatment of severe anterior open bite with skeletal anchorage in adults: Comparison with orthognathic surgery outcomes. Am J Orthod Dentofacial Orthop, 132:599-605.

Takano-Yamamoto T, Kuroda S. (2007): Titanium screw anchorage for correction of canted occlusal plane in patients with facial asymmetry. Am J Orthod Dentofacial Orthop, 132:237-242.

Kuroda S, Yanagita T, Kyung HM, Takano-Yamamoto T. (2007): Titanium screw anchorage for traction of many impacted teeth in a patient with cleidocranial dysplasia. Am J Orthod Dentofacial Orthop, 131:666-669.

Kuroda S, Yamada K, Deguchi T, Hashimoto T, Kyung HM, Takano-Yamamoto T. (2007): Root proximity is a major factor for screw failure in orthodontic anchorage. Am J Orthod Dentofacial Orthop, 131:S68-73.

Kuroda S, Sugawara Y, Tamamura N, Takano-Yamamoto T. (2007): Anterior open bite with temporomandibular disorder treated with titanium screw anchorage: Evaluation of morphological and functional improvement. Am J Orthod Dentofacial Orthop, 131:550-560.

Kuroda S, Sugawara Y, Deguchi T, Kyung HM, Takano-Yamamoto T. (2007): Clinical use of miniscrew implants as orthodontic anchorage: success rates and postoperative discomfort. Am J Orthod Dentofacial Orthop, 131:9-15.

Fukunaga T, Kuroda S, Kurosaka H, Takano-Yamamoto T. (2006): Skeletal anchorage for orthodontic correction of maxillary protrusion with adult periodontitis. Angle Orthod, 76:148-155.

Kuroda S, Sugawara Y, Yamashita K, Mano T, Takano-Yamamoto T. (2005): Skeletal Class III oligodontia patient treated with titanium screw anchorage and orthognathic surgery. Am J Orthod Dentofacial Orthop, 127:730-738.

Kuroda S, Araki Y, Oya S, Mishima K, Sugawara T, Takano-Yamamoto T. (2005): Maxillary distraction osteogensis to treat maxillary hypoplasia: Comparison of an internal and an external system. Am J Orthod Dentofacial Orthop, 127:493-498.

Kuroda S, Kuroda Y. (2005): Nonextraction treatment of upper canine-premolar transposition in an adult patient. Angle Orthod, 75:421-426.

Kuroda S, Balam TA, Sakai Y, Tamamura N, Takano-Yamamoto T. (2005): Expression of osteopontin mRNA in odontoclasts revealed by in situ hybridization during experimental tooth movement in mice. J Bone Miner Metab, 23:110-113.

Kuroda S, Katayama A, Takano-Yamamoto T. (2004): Severe anterior open-bite case treated using titanium screw anchorage. Angle Orthod, 74:558-567.

Kuroda S, Kuboki T, Katayama A, Takano-Yamamoto T. (2003): Use of a porcelain laminate veneer for esthetic improvement after orthodontic treatment. Orthod Waves, 62:437-438.

Minato M, Miyawaki S, Tanimoto Y, Kuroda S, Yasuda Y, Takano-Yamamoto T. (2002): An adult case untreated for 7 years after loss of the mandibular left first molar. Orthod Waves, 61:466-470.

Kawakami M, Kuroda S, Yoshida CA, Yamashita K, Takada K. (2000): Dental follicle cell-conditioned medium enhances the formation of osteoclast-like multinucleated cells. Eur J Orthod , 22:675-682.

Kawakami M, Kuroda S, Yamashita K, Yoshida CA, Nakagawa K, Takada K. (1999): Expression of CSF-1 receptor on TRAP-positive multinuclear cells around the erupting molars in rats. J Craniofac Genet Dev Biol, 19:213-220.